| ncRNA name | hsa-miR-106b |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples and adjacent noncancerous tissues; RB cell line WERI-RB1 |
| Methods | qRT-PCR, CCK-8 assay, transwell assay, Western blot, luciferase reporter assay |
| Expression pattern | up-regulated |
| Functional description | Increased expression of miR-106b in RB tissues is positively associated with the metastasis and differentiation of RB cells. As an oncogene, miR-106b promotes the proliferation, migration and invasion of WERI-Rb-1 cells by inhibiting the expression of ZBTB4 protein. |
| PubMed ID | 30542402 |
| Year | 2018 |
| Title | MicroRNA-106b promotes the proliferation, migration and invasion of retinoblastoma cells by inhibiting the expression of ZBTB4 protein. |
| Drug-related ncRNA | NO |
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